Non-invasive genetic tests

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Genetic testing has many implications in medicine and personal health management:

Personal health management: 

Certain genetic variants may affect a person's response to exercise and specific nutrients. This can help to develop personalized exercise plans and dietary regimens.

Genetic counseling and family planning: 

For family planning or pregnancy, genetic testing can provide genetic counseling to help people understand the risks of the genes they carry and make more informed decisions for future family planning.

Prevention and early diagnosis: 

Genetic testing can help identify the risk of having an inherited disease, thus facilitating early intervention and preventive measures. By identifying potential risks of genetic diseases, people can take steps to reduce the likelihood of developing the disease or treat the disease at an early stage of its appearance to improve treatment outcomes.

Personalized medicine: 

Genetic testing can provide individual genetic information that can help develop personalized healthcare plans. Knowledge of an individual's genetic information can help physicians select treatments or drug types and dosages more accurately to improve efficacy and reduce the risk of adverse effects for certain diseases or drug reactivity. 

EboGenes, powered by Ebovir, offers the following genetic testing services:

Option A1:  Based on the latest version of the human reference genome, we conduct NGS whole gene sequencing on users, and analyze genes of interest, the user can choose any 10 test reports from our programs.

Option A2:  According to the latest version of the human reference genomes, we conduct NGS whole genome sequencing, and analyze genes of interest, the user can choose any 10 test reports from our programs.

Option A3:  We customized genetic analysis according to users’ request, and provide test reports for the tested genes. 

Beside A1 options, A3 also includes following tests:

Obesity genetic testing (WES);

Reproductive health genetic screening (Couple);

Hereditary Breast and Ovarian Cancer Syndrome (WES);

Rheumatoid arthritis (WES);

Type 2 diabetes (WES);

Hereditary cancer screening (Related Multiple Genes Panel test);

Drug indication (Related Multiple Genes Panel test);

Tailored Family genmic study services.

• Common Genetic Disorders 

 Common genetic disorders diseases are conditions in which certain diseases or symptoms are more common in the family or are more likely to be passed on to offspring. These disorders may result from mutations or variations, or inheritance of specific genes that increase the risk of developing the disease.

A common genetic disorders report can provide an assessment of an individual's risk of developing a specific inherited disease, helping people to understand their risk of developing the disease, helping individuals and families to plan an early treatment or intervention when necessary. Early intervention can help to alleviate symptoms, reduce the risk of the disease, and improve quality of life. 

• Hereditary Cancer

Hereditary cancers are mainly tested for genes associated with cancers that occur in adulthood. Hereditary cancers are heterogeneous and they mainly affect organs such as the breast, ovary, uterus, prostate and gastrointestinal tract. And it is insufficient to determine the cause by the clinical assessment. A genetic testing is effective in examining multiple genes involved in clinical symptoms. Genetic analysis of these genes can help to confirm the diagnosis of clinical symptoms, predict the course of the disease, detect symptoms early, guide family planning and genetic counseling, anddetermine eligibility for clinical studies.

• Drug Indications

Drug indication genetic screening is a method of analyzing an individual's genetic information to understand their possible responses to specific medications. Genes can influence their absorption, metabolism, delivery and excretion of medications, which in turn can affect their efficacy and possible side effects.

Through genetic screening, specific gene variants can be identified that are associated with key enzymes or proteins in the drug metabolism pathway. This information can help physicians better select the most appropriate drug type, dosage, and treatment to improve therapeutic efficacy and reduce the risk of adverse effects.

• Rare Genetic Disorders

Rare genetic disorder diagnosis refers to the diagnosis of diseases suffered by a very small amount of people in the population. Genetic testing for rare genetic disease includes: phenylketonuria, thalassemia major, osteogenesis imperfecta, mucopolysaccharidoses, Wilson's disease. And genetic analysis for more than 2,000 rare genetic diseases can be customized if needed.

• Cardiovascular Disease

Genetic screening for cardiovascular disease assesses a person's risk of developing cardiovascular disease by analyzing an individual's genetic information. Cardiovascular diseases involve the heart and vascular system and include coronary heart disease, hypertension, myocardial infarction, atherosclerosis, and hypertrophic cardiomyopathy (HCM). Genetic factors play a role in the pathogenesis of cardiovascular disease, so genetic screening can help to understand the risk of developing cardiovascular disease. Genetic screening for cardiovascular diseases can provide information for personalized medicine and help in the development of early intervention and preventions.

• Neurodegenerative Diseases

Neurodegenerative diseases are a group of disorders that affect the nervous system, resulting in the gradual degeneration or death of nerve cells, which ultimately affects the body's motor, sensory, or cognitive functions. These diseases may vary in symptoms, rate of progression, and the part of the nervous system affected.

They are often caused by a combination of genetic mutations, environmental factors, or other unknown factors, and diagnosis and treatment remain a challenge for most neurodegenerative diseases. Treatment for these disorders tends to be symptomatic and currently there is no cure in most cases,. Genetic testing can provide information in the risk of developing neurodegenerative diseases and precision medicine of patients, helping us and clinicians make decisions in early diagnosis, prevention and treatment. Early diagnosis and treatment can help relieve symptoms, slow disease progression, and improve quality of life for patients.

• Reproductive Health (Single)

Reproductive health genetic screening is a comprehensive genetic test for fertility, designed to identify mutations or changes in the genes that may affect their reproductive health or the health of offspring. This type of screening is vital for pregnancy, as it can provide valuable information about genetic disorders that may be passed on to children.

Screening typically covers a range of genetic disorders, including fertility-related disorders, chromosomal abnormalities, inherited disorders, and other disorders that may affect pregnancy or the long-term health of the child. Screening results can help individuals and couples make informed decisions about family planning, such as whether to use assisted reproductive technologies, prenatal testing, or genetic counseling. 

• Diseases of the Immune System

Immune system disorders are abnormalities in the immune system that result in an abnormal immune response to one's own tissues or substances. The function of the immune system is to protect the body from pathogens (e.g., bacteria, viruses, etc.). When there is a dysregulation of the immune system, it may attack normal tissues of the body, leading to a range of diseases.

Genetic testing can help us diagnose primary immunodeficiencies and autoinflammatory/autoimmune diseases. The result of genetic testing can be decisive for further clinical patient management such as vaccinations, medication, and transplantation.

• Metabolic Diseases

Metabolic diseases are disorders related to the body's metabolic processes, usually involving energy balance, hormone regulation and substance transformation. These disorders may affect the body's energy utilization, hormone balance, or metabolism of specific substances, leading to a range of health problems. Approaches to managing metabolic diseases include medication, lifestyle changes such as dietary habits and exercise, and monitoring and managing potential complications. Prevention and early intervention are critical to the management of these disorders, as they are often associated with the development of many chronic diseases and complications.

Genetic testing is the most effective method for categorizing metabolic disorders and offers the essential details required for making informed decisions about personalized treatment and management. Detecting family members who are at risk enables the initiation of preventative therapies and/or the suggestion of lifestyle modifications.

• Nutrigenomic Test

Nutrigenetic analysis offers a revolutionary approach to personalized dietary planning, harnessing the power of genetic science to tailor nutrition to individual needs. By understanding these unique genetic factors, the service provides personalized dietary recommendations that empower individuals to optimize health and wellness through nutrition.

Nutrigenomic Precision Analysis provides customized nutritional strategies that take into account individual genetic variations that affect how an individual's body processes vitamins, fats, carbohydrates, and proteins. This analysis is especially beneficial for those looking to improve overall health, manage specific health issues, or improve athletic performance.

• Anti-Aging Genes

The Anti-Aging Gene Analysis is an innovative genetic test designed to explore genes associated with aging and longevity. The analysis includes research to discover selected genetic markers associated with age change and disease. The test delves into genetic variants that may affect an individual's lifespan, susceptibility to age-related diseases, and overall healthy longevity. For those who wish to better understand their genetic aging process and for professionals who are developing targeted interventions to promote healthy aging, an anti-aging genetic analysis can assist them in making informed decisions about their health and longevity.

• Skin Health Genes 

Skin care genetic testing is a method of analyzing an individual's genomic information to understand skin characteristics, skin care needs, and predict possible skin problems. These genetic tests can provide information about skin characteristics such as skin elasticity, antioxidant capacity, moisturizing capacity, and pigmentation tendencies. By knowing this genetic information, people can better choose skin care products that suit their skin characteristics, adjust their skin care habits, and prevent possible skin problems.

• Genetic Screening for Obesity (WES)

An in-depth genetic evaluation targeting 41 genes associated with monogenic obesity will be conducted. This advanced screening is critical for diagnosing and guiding the treatment of patients with obesity due to monogenic mutations. The results of this comprehensive test include extensive interpretation of detected genetic variants, helping healthcare providers make informed decisions about patient care. Obesity genetic analysis is an indispensable genetic testing tool that greatly improves the people's understanding of monogenic obesity.

• Reproductive Health (Couple)

Reproductive health genetic screening for couples refers to genetic testing of potential parents to understand their genetic information and the risk of potential genetic diseases. The outcome of the genetic analysis can be used to minimize the risk of genetic diseases that may be passed on to their offspring before or during pregnancy. If the test results indicate that a couple is at risk of carrying certain genetic diseases, they may choose to undergo pre-pregnancy diagnosis, assisted reproductive technology or preimplantation genetic screening to minimize or avoid the risk of passing on potential genetic diseases to their offspring.

• Hereditary Breast and Ovarian Cancer (WES)

We perform genetic analysis on around 100 mutations of the BRCA1 and BRCA2 genes, which significantly increase the risk of breast cancer in individuals carrying the disease-causing variants. When the tested individual is diagnosed with the disease, genetic testing results can help doctors choose treatments to target BRCA1 and BRCA2 variants. It can also be used to assist in diagnosis and treatment for family members who may be at risk.

• Rheumatoid Arthritis (WES)

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of the joints, often resulting in swelling, pain, stiffness and dysfunction. The disease typically affects multiple joints, particularly the fingers, wrists, knees and ankles. Early genetic diagnosis and treatment is essential to control inflammation, reduce symptoms, prevent joint damage and improve quality of life.

• Type 2 Diabetes (WES)

Type 2 diabetes is a chronic metabolic disease characterized by the body's resistance to insulin and insufficient insulin production, resulting in elevated blood sugar. Usually occurring in adults, but also increasing in recent years in adolescents and children, type 2 diabetes is often associated with lifestyle and genetic factors. Early diagnosis and aggressive treatment are important to prevent complications, manage symptoms and improve quality of life.