Hereditary breast and ovarian cancer syndrome (HBOC)

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BRCA2, BARD1, ATM, CHEK2, PALB2, PTEN, TP53, FGFR2, TNRC9

Our breast cancer genetic testing includes the above genes because they are known to be related to breast cancer, as identified by the National Cancer Institute (NCI).

 This test analyzes the BRCA1 and BRCA2 genes, including around 100 mutants. Individuals carrying a pathogenic variant are at an increased risk of developing additional breast cancer. Consequently, they might opt for more extensive surgical procedures or alternative treatment choices, influenced by the outcomes of their genetic testing. Established medical management guidelines are in place for BRCA1 and BRCA2 variants. Discovering a variant responsible for the disease can also inform the testing and treatment approaches for family members who may be at risk.