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免疫系统基因检测
免疫系统基因检测
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基因在决定身体如何应对感染方面起着至关重要的作用。基因变异会影响免疫系统抵抗病毒、细菌和其他病原体的能力。本检测旨在探讨基因检测如何洞察您的感染风险，指导预防性医疗保健策略，并帮助管理自身免疫性疾病或特定感染易感性等疾病。
背景
为什么有些人感染后病情严重，而另一些人却只出现轻微症状或完全没有症状？答案通常在于他们的基因构成。你的免疫系统天生就具备识别和应对病原体的基因编程，但某些基因的变异会影响你的身体抵抗感染的能力。这些基因差异可以解释为什么有些人更容易感染某些感染，例如流感、新冠肺炎 (COVID-19) 或结核病，而另一些人则天生具有更强的抵抗力。通过了解你的基因如何影响你的感染风险，你可以采取积极主动的措施来增强免疫力，制定你的医疗保健计划，并降低患重病的可能性。
技术概述
· SNP分析：单核苷酸多态性 (SNP) 是影响免疫系统功能的基因变异。通过分析与免疫反应相关的基因（例如 HLA（人类白细胞抗原）基因和 IFNL3（干扰素 λ3））的 SNP，我们可以评估您对病毒或细菌感染的易感性。
· 免疫系统基因：像TLR（Toll样受体）这样的基因在检测病原体和激活免疫反应中起着至关重要的作用。这些基因的变异会影响身体对感染的反应速度和效果。
· 细胞因子反应：细胞因子是调节免疫反应的蛋白质。IL6（白细胞介素-6）和TNF（肿瘤坏死因子）等基因会影响细胞因子的产生，这些细胞因子既可以帮助控制感染，也可能导致过度炎症，从而引发严重症状。
All 6.4 billion letters of your DNA — read, stored, and yours to keep.
Most consumer DNA tests sample a few hundred thousand positions. Whole genome sequencing reads the entire thing at 30× depth, and hands you the files at the end. No subscription required to keep them.
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30×
average
coverage depth -
6.4B
base pairs
sequenced -
FASTQ
BAM & VCF
files included
How it runs
Kit arrives
Day 0，Saliva collection takes about five minutes. Avoid eating, drinking, or brushing your teeth for thirty minutes beforehand — that's the only preparation required.
Sample ships back
Day 1–2， Prepaid return envelope is included. Saliva samples are stable at room temperature, so there's no cold chain to manage on your end.
DNA extraction and quality check
Week 1，We extract and assess DNA quality before sequencing. If a sample fails QC, we send a replacement kit at no charge rather than sequencing something that won't yield reliable calls.
Sequencing and analysis
Week 2–6，Sequencing, alignment to GRCh38, and variant calling. This is the longest stage and we'd rather state it accurately than quote a number we miss.
Reports and files released
Week 2–6， Your reports and all three file formats become available together. You'll get an email the moment they're ready.
No. Ebogenes whole genome sequencing is offered for research and personal informational use. It is not a diagnostic test, it is not a substitute for clinical genetic testing, and it should not be used to make medical decisions on its own. If a finding concerns you, bring it to a physician or a certified genetic counsellor — that's what the files are for.
Each position in your genome is read approximately thirty times on average. Sequencing makes errors, so reading a position once tells you little; reading it thirty times lets a variant call rest on consensus. 30× is the widely used standard for reliable variant calling — below it, calls get noticeably less dependable.
Our reports flag findings for follow-up; they do not diagnose. A variant of uncertain significance is a flag, not a finding — many are later reclassified as benign. We'd rather tell you plainly that something needs a professional look than dress up an uncertain result as an answer.
Sequencing and storage happen at our Laval, Québec facility. Your data stays in Canada and is subject to Canadian privacy law. We do not sell your genetic data, and we do not share it with insurers, employers, or research programmes without your explicit, separate consent. You can request deletion at any time.
No. Your reports and all three file formats remain accessible without any ongoing payment. Download them and store your own copy if you prefer — that's the point of giving you FASTQ.