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Immune System Genetic Testing
Immune System Genetic Testing
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Your genes play a crucial role in determining how your body responds to infections. Genetic variations can influence your immune system's ability to fight off viruses, bacteria, and other pathogens. This test explores how genetic testing can provide insights into your infection risk, guide preventive healthcare strategies, and help in managing conditions such as autoimmune diseases or susceptibility to specific infections.
Background
Why do some people get severely ill from infections while others experience only mild symptoms or none at all? The answer often lies in their genetic makeup. Your immune system is genetically programmed to recognize and respond to pathogens, but variations in certain genes can affect how well your body fights infections. These genetic differences can explain why some individuals are more susceptible to certain infections, such as the flu, COVID-19, or tuberculosis, while others are naturally more resistant. By understanding how your genes influence your infection risk, you can take proactive measures to boost your immunity, tailor your healthcare plan, and reduce the likelihood of severe illness.
Technology Overview
· SNP Analysis: Single Nucleotide Polymorphisms (SNPs) are genetic variations that affect immune system function. By analyzing SNPs in genes involved in immune response, such as HLA (human leukocyte antigen) genes and IFNL3 (interferon lambda 3), we can assess your susceptibility to viral or bacterial infections.
· Immune System Genes: Genes like TLR (Toll-like receptors) play a critical role in detecting pathogens and activating immune responses. Variants in these genes can affect how quickly and effectively your body responds to infections.
· Cytokine Response: Cytokines are proteins that regulate the immune response. Genes like IL6 (interleukin-6) and TNF (tumor necrosis factor) influence the production of cytokines, which can either help control an infection or lead to excessive inflammation, contributing to severe symptoms.
All 6.4 billion letters of your DNA — read, stored, and yours to keep.
Most consumer DNA tests sample a few hundred thousand positions. Whole genome sequencing reads the entire thing at 30× depth, and hands you the files at the end. No subscription required to keep them.
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30×
average
coverage depth -
6.4B
base pairs
sequenced -
FASTQ
BAM & VCF
files included
How it runs
Kit arrives
Day 0，Saliva collection takes about five minutes. Avoid eating, drinking, or brushing your teeth for thirty minutes beforehand — that's the only preparation required.
Sample ships back
Day 1–2， Prepaid return envelope is included. Saliva samples are stable at room temperature, so there's no cold chain to manage on your end.
DNA extraction and quality check
Week 1，We extract and assess DNA quality before sequencing. If a sample fails QC, we send a replacement kit at no charge rather than sequencing something that won't yield reliable calls.
Sequencing and analysis
Week 2–6，Sequencing, alignment to GRCh38, and variant calling. This is the longest stage and we'd rather state it accurately than quote a number we miss.
Reports and files released
Week 2–6， Your reports and all three file formats become available together. You'll get an email the moment they're ready.
No. Ebogenes whole genome sequencing is offered for research and personal informational use. It is not a diagnostic test, it is not a substitute for clinical genetic testing, and it should not be used to make medical decisions on its own. If a finding concerns you, bring it to a physician or a certified genetic counsellor — that's what the files are for.
Each position in your genome is read approximately thirty times on average. Sequencing makes errors, so reading a position once tells you little; reading it thirty times lets a variant call rest on consensus. 30× is the widely used standard for reliable variant calling — below it, calls get noticeably less dependable.
Our reports flag findings for follow-up; they do not diagnose. A variant of uncertain significance is a flag, not a finding — many are later reclassified as benign. We'd rather tell you plainly that something needs a professional look than dress up an uncertain result as an answer.
Sequencing and storage happen at our Laval, Québec facility. Your data stays in Canada and is subject to Canadian privacy law. We do not sell your genetic data, and we do not share it with insurers, employers, or research programmes without your explicit, separate consent. You can request deletion at any time.
No. Your reports and all three file formats remain accessible without any ongoing payment. Download them and store your own copy if you prefer — that's the point of giving you FASTQ.